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The stage is set for a compelling Premier League matchup as front-runners Arsenal welcome bottom-placed Wolverhampton Wanderers to the their home ground.

Starting Lineups

Mikel Arteta's side have opted for three changes from the XI that endured a 2-1 loss at Villa Park last weekend. William Saliba, Viktor Gyökeres and Gabriel Martinelli all start in the lineup. Martin Ødegaard and the Spanish midfielder are named on the substitutes' bench, while the Italian defender is absent. The centre-back returns after missing five matches due to injury.

The visitors also make three changes to their lineup after being soundly beaten 4-1 at Molineux by United on Monday evening. The experienced full-back, João Gomes and Hwang Hee-chan come in. Ki-Jana Hoever and Arias drop to the substitutes, while Bellegarde is omitted altogether.

The Teams in Full

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Subs: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Bench: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Match Official: Robert Jones
VAR Official: John Brooks

The Setup

Good evening! Because, c’mon …

The standings paints a striking picture. Arsenal sit proudly at the top of the table, while Wolves occupy the bottom of the league.

… however, even though this will be the 42nd occasion the top side have played the side propping up the entire table – with 30 victories from 41, with seven tied games – which team is responsible for two of the four all-time upsets? Why, Wolverhampton Wanderers, of course! Therefore, although the Arsenal manager will surely be expecting another three points, the Wolves boss must know that underdogs occasionally find the target, and you never know. The start is at 8pm GMT. Let's go!

^{(The other two last-over-first wins in the Premier League era are Oldham Athletic's 1-0 win over United in March 1993, and Tottenham Hotspur – admittedly, this one sounds a bit weird - defeating Liverpool in November 2008.)}